SkinSelfRenewal Blog

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Nam Dang, from University of Florida (USA), and colleagues studied extracts of papaya leaf to ascertain the cellular mechanism of action of its potential role in inhibiting the growth of tumor cell lines. The team found that four strengths of papaya leaf extract slowed the growth of ten types of cancer cell cultures, including cancers of the cervix, breast, liver, lung and pancreas. Positing that the papaya may beneficially alter the immune system, the researchers write that: “… papaya leaf extract can mediate a Th1 type shift in human immune system …[Papaya] leaf extract may potentially provide the means for the treatment and prevention of selected human diseases such as cancer.

Nitrosation is a cellular process in which substances in foods and the water are converted into cancer-causing compounds. Earl H. Harrison, from Ohio State University and colleagues developed a new urine test that measures for compounds related to cancer risk while detecting the levels of N-nitrosoproline and N-acetyl-S-allylcysteine, compounds abundantly present in garlic. The team found that the greater the markers of garlic compounds, the less strongly they found the marker for cancer risk. Writing that “3 to 5 grams of garlic supplements inhibited [Nitrosoproline] NPRO [excretion],” a key marker of nitrosation, the researchers observe that: “It is possible that allyl sulfur compounds found in garlic may inhibit nitrosation in humans.” Posted on 2010-03-22 06:00:00 in Cancer | Functional Foods